Resumen

MEJIA, N. et al. Chronic kidney disease-mineral and bone disorder: a complex scenario. Nefrología (Madr.) [online]. 2011, vol.31, n.5, pp.514-519. ISSN 1989-2284.

The chronic kidney disease-bone and mineral disorders (CKD-MBD) represents a dinamic area of research. Recently, new factors such as FGF-23 have been added to the classic list of regulators of bone metabolism, which include calcium, phosphorus, PTH and calcitriol. Vascular calcification, one of the most important complication of CKD-MBD is regulated by a complex variety of promoters and inhibitors. The relationship between vascular calcification, bone loss and mortality, together with the existence of likely common signaling pathways are subject of interesting investigations.

Palabras clave : CKD-MBD; Vascular calcification; FGF-23; Bone demineralization; Secondary hyperparathyroidism.

        · resumen en Español     · texto en Español     · Español ( pdf )