Abstract

GONZALEZ AVILA, G.; RODRIGUEZ OVALLE, H.  and  ROJAS BARRERA, J. A.. Morbidity and mortality from ileal duct and its relationship with post-surgical total parenteral nutrition. Nutr. Hosp. [online]. 2006, vol.21, n.4, pp.511-516. ISSN 1699-5198.

Background: The frequency of complications and early death in patients with hyponutrition and total radical cystectomy with ileal duct is high. The role of artificial nutritional support on short-term outcomes is still controversial. Objective: to determine whether total parenteral nutrition reduces the frequency of complications and death when it is administered during the immediate post-surgical period. Design: cohort study. Setting: third-level reference hospital. Subjects: One hundred and fourteen consecutive patients having radical cystectomy and ileal duct between January of 2000 and June of 2004. Interventions: Eight-one patients received post-surgical total parenteral nutrition for an average of 9.2 days, and 33 controls received 5% dextrose solution + 0.9% saline solution. Main results and measurements: thirty-six (31.6%) patients had complications and 11 (9.6%) died. The main death-related complications were of surgical origin.After a multiple regression multivariate analysis, and according to risk and nutritional intervention, an important reduction of early death was found in the group with severe hyponutrition (RR = 0.09; 95% CI =0.02-0.33; p = 0.008). Anastomosis dehiscence in the presence of abdominal sepsis was the most important predictive factor of early death (RR = 5.0; 95% CI = 1.45-17.3; p = 0.007). Conclusions: The group with no hyponutrition or with mild hyponutrition does not benefit from post-surgical total parenteral nutrition.

Keywords : Post-surgical total parenteral nutrition; Cystectomy; Ileal duct.

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