SciELO - Scientific Electronic Library Online

vol.26 issue2Intervention programs to promote physical activity in school children: systematic reviewRetinol, β-carotene, α-tocopherol and vitamin D status in European adolescents; regional differences an variability: A review author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Nutrición Hospitalaria

On-line version ISSN 1699-5198Print version ISSN 0212-1611


VIANA ABRANCHES, M.; ESTEVES DE OLIVEIRA, F. C.  and  BRESSAN, J.. Peroxisome proliferator-activated receptor: effects on nutritional homeostasis, obesity and diabetes mellitus. Nutr. Hosp. [online]. 2011, vol.26, n.2, pp.271-279. ISSN 1699-5198.

The obesity and the metabolic disorders associated characterize the metabolic syndrome, which has increased at an alarming rate around the world. It is known that environmental and genetic factors are involved in the genesis of obesity. Peroxisome Proliferator-Activated Receptors (PPARs) stand out among these factors. They compose the nuclear receptor superfamily and there are in three isoforms (PPARα,PPARβ/δ and PPARγ), which play an important role in the regulation of the metabolism of carbohydrates, lipids and proteins. The present review aims to understand the relationship between the diet, the PPARs and the control of the blood glucose and body weight, since the understanding about the mechanisms by which these receptors act may benefit the development of the strategies aiming at prevention and elaboration of therapeutics actions which are more effective for the treatment of obesity and diabetes.

Keywords : Peroxisome Proliferator-Activated Receptors; Obesity; Diabetes Mellitus; Metabolism.

        · abstract in Spanish     · text in English     · English ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License