SciELO - Scientific Electronic Library Online

vol.30 número6¿Es el gluten el gran agente etiopatogénico de enfermedad en el siglo XXI? índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados




Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google


Nutrición Hospitalaria

versão On-line ISSN 1699-5198versão impressa ISSN 0212-1611


FELICIANO PEREIRA, Patricia; ELOIZA PRIORE, Silvia  e  BRESSAN, Josefina. Aldosterone: a cardiometabolic risk hormone?. Nutr. Hosp. [online]. 2014, vol.30, n.6, pp.1191-1202. ISSN 1699-5198.

Introduction: A aldosterone is a component of the renin-angiotensin-aldosterone system, classically known for its role in sodium and water retention. Besides its effects, has been shown that the aldosterone is associated with the pathogenesis and progression of metabolic syndrome components. A better understanding of this system and interfering factors could help develop pharmacotherapeutic alternatives for several disorders. Objectives: Investigate the relationship between diet and aldosterone, and its influence on cardiometabolic risk factors. Results and Discussion: Diet can affect plasma aldosterone levels; high fructose and fat intake can lead to increased aldosterone levels, whereas the effect of sodium intake remains controversial. Adipose tissue, particularly visceral tissue, appears to produce a lipid-soluble factor that increases aldosterone production. Patients with metabolic syndrome have higher aldosterone levels; moreover, an increased cardiometabolic risk associated with insulin resistance could be partially mediated by the action of aldosterone via mineralocorticoid receptors. Even a subtle activation of this hormonal system may have deleterious effects on the glucose and lipid metabolism related to metabolic syndrome. Nevertheless, additional studies are required to better understand the interactions among adipose tissue, aldosterone, and cardiovascular risk as well as the possible role of diet.

Palavras-chave : Aldosterone; Obesity; Metabolic syndrome; Cardiovascular diseases.

        · resumo em Espanhol     · texto em Inglês     · Inglês ( pdf )