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Nutrición Hospitalaria

On-line version ISSN 1699-5198Print version ISSN 0212-1611


CASTILLO, Natalia Del et al. Perinatal outcomes of prematurity and birth weight according to maternal caffeine consumption. Nutr. Hosp. [online]. 2015, vol.32, n.6, pp.2658-2664. ISSN 1699-5198.

Objetive: identify whether there is an increased risk of adverse perinatal outcomes, like prematurity or decreased weight in newborns, associated with caffeine consumption during the first half of pregnancy in pregnant women of our population. Methods: transversal study carried out in 1 175 patients from Virgen de las Nieves University Hospital of Granada (Spain). Information about caffeine consumption during first half of gestation and perinatal outcomes was obtained by personal interview, medical records and telephone call after delivery. The average caffeine intake was calculated from meals and drinks included in a validated questionnaire. Results: there was no difference in caffeine consumption in pregnant women with birth weight .2 500 g and <2 500 g, or in pregnant women with newborns appropriate for gestational age and small for gestational age, or in pregnant women with term and preterm delivery. When studying the birth weight as a dependent variable, adjusted for confounding variables, a significant association (p <0.05) with decreased birth weight was found (-87.7; 95% CI -159.8, -15.6 g) for caffeine consumption in the fourth quartile (115.01-650 mg/day). Conclusions: there is no relation between caffeine intake and low birth weight, small for gestational age or prematurity, but a decrease in birth weight of mothers who consume large amounts of caffeine is observed.

Keywords : Caffeine; Perinatal outcomes; Birth weight; Prematurity.

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