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Nutrición Hospitalaria

On-line version ISSN 1699-5198Print version ISSN 0212-1611


FERNANDEZ-ARAQUE, Ana; GIAQUINTA-ARANDA, Andrea; LAUDO-PARDOS, Consuelo  and  ROJO-ARAGUES, Abel-A.. The antioxidants in the process of ocular pathology. Nutr. Hosp. [online]. 2017, vol.34, n.2, pp.469-478. ISSN 1699-5198.


The influence of antioxidants on ocular processes has taken on a significant importance in recent years for its effects on visual health. Oxidative stress is a factor involved in the development of major pathologies such as cataracts, glaucoma and age-related macular degeneration (AMD).


To establish the scientific evidence that exists about the different types of antioxidants and their effects on ocular pathological processes through a systematic review.


Literature search in MEDLINE, Scielo and Cochrane for studies evaluating the use of antioxidants in the prevention and/or treatment of eye diseases. Selected randomized controlled clinical trials over the past 7 years were selected.


The relationship between different types of antioxidants, vitamin E, C, beta carotene, zinc, lutein, anthocyanins and carotenoids, suggests a positive relationship with the risk and progression of AMD and glaucoma parameters, indicating a lower risk of the disease due to an increased consumption of antioxidants in the diet. Initial reports suggest a potential role for diet modification in the treatment of age-related macular degeneration and glaucoma primarily, not evidencing for the prevention of cataract.


Promoting adequate consumption of antioxidants in the diet can prevent and protect against highly prevalent eye diseases. The antioxidants of the group of vitamins are the most studied so far in the ocular pathologies. More clinical trials are needed to establish these relationships more precisely.

Keywords : Antioxidant; Glaucoma; Macular degeneration; Cataract; Effectiveness.

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