My SciELO
Services on Demand
Journal
Article
Indicators
- Cited by SciELO
- Access statistics
Related links
- Cited by Google
- Similars in SciELO
- Similars in Google
Share
Nutrición Hospitalaria
On-line version ISSN 1699-5198Print version ISSN 0212-1611
Abstract
LIMA, Carlos Henrique Ribeiro et al. Effects of vitamin D supplementation on the glycemic control of pre-diabetic individuals: a systematic review. Nutr. Hosp. [online]. 2021, vol.38, n.1, pp.186-193. Epub Apr 26, 2021. ISSN 1699-5198. https://dx.doi.org/10.20960/nh.03309.
Introduction:
research shows the potential effect of vitamin D supplementation with an improvement in the glycemic profile of pre-diabetic patients.
Objective:
this study evaluates the effects of vitamin D supplementation on glycemic control markers in pre-diabetic individuals.
Methods:
we analyzed studies published over the last ten years, and indexed in the Science Direct, PubMed, and LILACS databases. We searched studies using health descriptors related to vitamin D, pre-diabetes, and glycemic control markers. We considered randomized controlled trials eligible for inclusion. All phases of selection, data extraction, and risk of bias assessment were carried out by two independent evaluators.
Results:
we identified 309 articles, of which 4 met the inclusion criteria. Of these, 3 studies have shown that vitamin D supplementation does not alter glycemic control markers in pre-diabetic individuals. Only one study showed a positive effect after supplementation with 60,000 IU/month of vitamin D3 for 12 months, with a significant reduction in the concentrations of glycated hemoglobin, fasting glucose, and two-hour postprandial glucose.
Conclusion:
there is insufficient scientific evidence to confirm the beneficial effects of vitamin D supplementation on glycemic control markers in pre-diabetic individuals.
Keywords : Vitamin D; Pre-diabetes; Fasting glucose; Insulin; Glycated hemoglobin A.