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Anales de Medicina Interna

versión impresa ISSN 0212-7199


VAL ANTONANA, A. del; ORTIZ POLO, I.; LOPEZ SERRANO, A.  y  MORENO-OSSET, E.. Treatment of hepatocellular carcinoma . An. Med. Interna (Madrid) [online]. 2002, vol.19, n.10, pp.43-48. ISSN 0212-7199.

Hepatocellular carcinoma develops in more of 90% of patients in the setting of cirrhosis. The increasing prevalence seems related with the wide-spread distribution of hepatitis C virus infection, as 80% of cases arise on chronic infection caused by this agent. Either conventional resection or orthotopic liver transplantation are often curative but suitable for few patients, If the surgical approach is not adequate, percutaneous ablation using ethanol injection or radiofrequency current may be considered. However, only 15-20% of patients can benefit from these therapies. Chemoembolization is considered when the previous options are contra-indicated but benefits on survival are still a matter of debate. The impact of new agents as tamoxifen, interferon o diverse chemotherapies on both survival and symptoms also remains to be stablished.

Palabras clave : Hepatocellular carcinoma; Cirrhosis; Treatment.

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