Abstract

GAVILAN, J. C. et al. Primary amyloidosis as a cause of severe intrahepatic cholestasis. An. Med. Interna (Madrid) [online]. 2003, vol.20, n.1, pp.33-35. ISSN 0212-7199.

The liver is frequently involved by amyloidosis, but hyperbilirubinemia and liver failure are uncommon features. A mild elevation of the serum alkaline phosphatase value and, less frequently, hepatomegaly are the most common findings. Usually the patients have no symptoms related with the liver involvement; the clinical manifestation and the long term prognosis depends on the renal and cardiac disease. We report an unusual clinical presentation of primary amyloidosis in a previously asymptomatic 65 years old woman who was admitted to the hospital because of ictericia and ascitis mimicking a drug induced acute hepatic failure.

Keywords : AL amyloidosis; Hepatic amyloidosis; Jaundice; Acute hepatic failure.

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