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Anales de Medicina Interna

Print version ISSN 0212-7199


LOPEZ SERRANO, P. et al. Extrahepatic portal hypertension: portal and splenic vein thrombosis secondary to protein C deficiency. An. Med. Interna (Madrid) [online]. 2003, vol.20, n.9, pp.35-38. ISSN 0212-7199.

Portal vein thrombosis (PVT) is the most frequent cause of hypertension portal extrahepatic. It is a rare disorder an the main risk factors are cirrhosis, hepatobiliary malignancies and prothrombotic disorders, which have been identified as major risk . Therapy with anticoagulants must to be considered in acute portal trombosis or chronic one and proven hypercoagulability. We present the case of a twenty-nine years old patient, with extrahepatic portal hypertension secondary to portal and splenic vein thrombosis, who was diagnosed because of splenomegaly and a coagulation disorder. A protein C deficiency were discovered and anticoagulation and beta-blocker therapy were iniciated. One year later the patient had not presented complications concerning to the disease or to the treatment.

Keywords : Hypertension portal; Portal vein thrombosis; Splenic thrombosis; Protein C defiency.

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