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Anales de Medicina Interna

versión impresa ISSN 0212-7199


BUSTAMANTE MALDONADO, E. et al. Analysis of a serie of 55 patients with biopsy proven giant cell temporal arteritis. An. Med. Interna (Madrid) [online]. 2004, vol.21, n.10, pp.11-14. ISSN 0212-7199.

Introduction: Our main aim with this study is to establish the epidemiologic and clinical features, treatment response and complications of a group composed of 55 patients with biopsy proven temporal arteritis in a local hospital. Material and methods: Restrospective study based on clinical records revision of patients diagnosticated of giant cell arteritis (GCA) made by temporal artery biopsy between 1989 and 2001. Results: The aproximated annual incidence of GCA in our area is 4.1 cases per 100.000 persons over the age of 50. The mean age at diagnostic was 74 years and the 78,2% were women. The most common symptom at diagnostic was headache (81,5%) followed by systemic manifestations (74,1%) and later we found jaw claudication (32,7%), visual impairment (30,2%), isquemic manifestations (17%). Polimyalgia rheumatica was asociated to GCA in 49,1% of cases. The temporal artery explorations was abnormal in the 76,9% of patients. The mean initial dose of corticoids was 69 mg prednisone per day, with a half dose reduction time of 3,5 months. In spite of that, 24,1% of patients relapsed during the first year. The 38% of patients did some complications during the corticosteroid treatment. The ESR was lower 50 mm in 12,7% of patients; it was anaemia in the 37,7% and thrombocitosis in 32,1%. In these last patients we detected a relation between thrombocitosis and specific visual impairment. Conclusions: The incidence of GCA in our area is low. The results of our serie aren't different from others publicated before in clinical manifestations, there is a prevalence of female sex and there is a relation between specific visual impairment and the presence of thrombocitosis.

Palabras clave : Temporal arteritis; Giant cell arteritis; Horton disease; Vasculitis; Temporal artery biopsy.

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