Abstract

CALVO ROMERO, J. M.. Troponin I in patients with pulmonary thromboembolism. An. Med. Interna (Madrid) [online]. 2005, vol.22, n.12, pp.589-590. ISSN 0212-7199.

Objective: To study the frequency in patients with pulmonary thromboembolism (PTE) of an elevated troponin I and the associated characteristics. Material and methods: Prospective study of 29 consecutive patients with PTE. Results: Troponin I was determined in 22 patients. The median age was 78.1 years. Ten (45.5%) had an elevated troponin I, with a median level of 1 ng/ml (range 0.7-3.1 ng/ml). The diagnostic delay was lower in patients with an elevated troponin I (2 ± 1.7 vs. 5.9 ± 5.6 days, p = 0.04). Three (30%) of 10 patients with an elevated troponin I had midthoracic pain. Patients with an elevated troponin I had a higher frequency of arterial hypotension (40 vs. 16.7%), respiratory failure (70 vs. 58.3%) and electrocardiographic overload right heart data (50% vs. 33.3%), although without reaching statistical significance. Conclusions: A slightly elevated troponin I is frequent in patients with PTE. The early diagnosis may increase the frequency of an elevated troponin I. The coexistence of an elevated troponin I and midthoracic pain may simulate an acute coronary syndrome. In patients with PTE, an elevated troponin I may associate to some severity criteria such as arterial hypotension, respiratory failure and electrocardiographic overload right heart data.

Keywords : Troponin; Troponin I; Pulmonary thromboembolism; Pulmonary embolism.

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