SciELO - Scientific Electronic Library Online

vol.29 número6Enucleación de odontoma compuesto maxilar con regeneración ósea guiadaPrevalencia de tumores odontogénicos en el Hospital Base Valdivia: periodo 1989-2008 índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados




Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google


Avances en Odontoestomatología

versão On-line ISSN 2340-3152versão impressa ISSN 0213-1285


MADERA ANAYA, M.V.. Salivary analysis of oral cancer biomarkers. Av Odontoestomatol [online]. 2013, vol.29, n.6, pp.293-302. ISSN 2340-3152.

This review shows the main oral cancer biomarkers in saliva. The clinical appearance and the degree of dysplasia, precancerous lesions of the oral cavity suggests its ability to malignancy, but these are usually diagnosed in advanced stages, decreasing the likelihood of survival, justifying the design of new diagnostic tests to determine the degree of cell alteration as to understand the degenerative process in cancer diagnosis and establish early. This search for improved diagnostic methods, aims to be sensitive, specific and less invasive, so the study of biomarkers in saliva from a molecular perspective provide additional information to clinical and histopathological examination is considered as a more comfortable and effective to establish a diagnosis. Biomarkers that have been described in saliva some showing more related to oral carcinogenesis are cyclin D1, Cyfra 21-1, Endothelin-1, Galectins 1, 3 and 7, Ki67, Lactate dehydrogenase, Metalloproteinases 2 and 9, p53 protein, protein calcium-binding (S100P) and Telomerase.

Palavras-chave : Oral cancer; biomarkers; saliva.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )


Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons