Abstract

ITURRIAGA, V.; BORNHARDT, T.  and  OPORTO, G.. Myofascial Pain in the craneocervical territory: a review of the pathology and its relationship with the GABAergic system genetic polymorphisms. Av Odontoestomatol [online]. 2015, vol.31, n.4, pp.267-271. ISSN 2340-3152.  https://dx.doi.org/10.4321/S0213-12852015000400004.

Myofascial pain is noninflammatory regional muscular disorder characterized by the presence of a muscle tissue area hyperirritable located on a taut band, called trigger point. In the orofacial region myofascial pain belongs to a cluster of diseases called temporomandibular disorder. Within these pathologies, it is to the most prevalent of its, clinical manifestations include local pain, muscle tension, structural dysfunction, referred pain, autonomic phenomena and hyperexcitability in the central nervous system. During the last decades have been associated genetic variants to painful pathologies, some of which are in the GABAergic system. This article performs a review of myofascial pain as pathology and its relation to genetic polymorphisms in GABAergic system.

Keywords : Myofascial pain syndromes; temporomandibular joint disorders; polymorphism; genetic; gamma-aminobutyric acid; receptors; GABA.

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