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Avances en Odontoestomatología

versão On-line ISSN 2340-3152versão impressa ISSN 0213-1285


LOPEZ SACRISTAN, H et al. Osteoinductive properties of the dentin in bone regeneration. Preliminary study. Av Odontoestomatol [online]. 2021, vol.37, n.1, pp.39-46.  Epub 05-Dez-2022. ISSN 2340-3152.


The concept of alveolar preservation is related to the procedures carried out after performing a tooth extraction in order to reduce resorption within the alveolus. Dentin has been proposed as a biomaterial for this purpose. The aim of this article is to evaluate the effectiveness of dentin in alveolar preservation and to contrast its properties.

Material and Method.

The first cases are presented as part of a work in progress study after multiple extractions. It is determined a study socket preserved with dentin and a control socket in which the clot is stabilized.The dimensional stability of both sockets was assessed by CBCT after 8 and 16 weeks. After this period, two experimental Bioecth® surface implants were placed. After 16 weeks these were explanted with trephine and replaced with conventional implants. The samples were analyzed histologically and histomorphometrically.


In the tomographic analysis it was observed greater dimensional stability on the study side. It was noted the absence of inflammatory cells, or signs of foreign body reaction in the histology. In addition, dentin particles were completely surrounded by newly formed bone, and appeared osteogenic fronts associated with these particles.


The results obtained from this study in humans are in line with what has been described in scientific papers. At the tomographic level, it was observed less dimensional variation in sockets where the preservation with particulate dentin was carried out. These results added to the histological análisis, contrast the properties described for particulate grafts of non-demineralized dentin, biocompatibility, osteoconduction and osteoinduction

Palavras-chave : Dentin; Bone-Implant Interface; Osseointegration; Bone Regeneration; Biocompatible Materials; Transplantation; Allografts; Alveolar Bone Grafting.

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