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Gaceta Sanitaria

Print version ISSN 0213-9111


RODRIGUEZ-MIGUEZ, Eva  and  MOSQUERA NOGUEIRA, Jacinto. Measuring the impact of alcohol-related disorders on quality of life through general population preferences. Gac Sanit [online]. 2017, vol.31, n.2, pp.89-94. ISSN 0213-9111.


To estimate the intangible effects of alcohol misuse on the drinker's quality of life, based on general population preferences.


The most important effects (dimensions) were identified by means of two focus groups conducted with patients and specialists. The levels of these dimensions were combined to yield different scenarios. A sample of 300 people taken from the general Spanish population evaluated a subset of these scenarios, selected by using a fractional factorial design. We used the probability lottery equivalent method to derive the utility score for the evaluated scenarios, and the random-effects regression model to estimate the relative importance of each dimension and to derive the utility score for the rest of scenarios not directly evaluated.


Four main dimensions were identified (family, physical health, psychological health and social) and divided into three levels of intensity. We found a wide variation in the utilities associated with the scenarios directly evaluated (ranging from 0.09 to 0.78). The dimensions with the greatest relative importance were physical health (36.4%) and family consequences (31.3%), followed by psychological (20.5%) and social consequences (11.8%).


Our findings confirm the benefits of adopting a heterogeneous approach to measure the effects of alcohol misuse. The estimated utilities could have both clinical and economic applications.

Keywords : Alcohol-related disorders; Quality-adjusted life years; Quality of life; Alcoholism; Focus groups.

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