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Gaceta Sanitaria

Print version ISSN 0213-9111


GUILLAUMES, Salvador  and  O'CALLAGHAN, Christopher A.. Spanish adaptation of the free OxMaR software for minimization and randomization of clinical studies. Gac Sanit [online]. 2019, vol.33, n.4, pp.395-397.  Epub Dec 02, 2019. ISSN 0213-9111.

Randomized clinical trials provide the highest level of scientific evidence. The method used for randomization should make the group to which each case will be assigned unpredictable and facilitate the concealment of the randomization sequence. Centralized methods, generally implemented with computer support, are considered the safest to avoid biases. The OxMaR system, acronym for Oxford Minimization and Randomization, was published as free and open source software in 2014. It works online in a web environment and allows simple randomization and adaptive assignment through minimization. We present a Spanish version developed in collaboration with the author of the original English version. The system has been modified to work on low cost shared web servers and also to allow the concealment of the randomization sequence.

Keywords : Random allocation; Randomized controlled trial; Software; Software design Web browser.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )