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Gaceta Sanitaria
Print version ISSN 0213-9111
Abstract
CHICO-SANCHEZ, Pablo and GRUPO COVID-19 DE MEDICINA PREVENTIVA et al. Effectiveness of BNT162b2 vaccine to preventing COVID-19 in healthcare personnel. Gac Sanit [online]. 2022, vol.36, n.5, pp.484-487. Epub Mar 13, 2023. ISSN 0213-9111. https://dx.doi.org/10.1016/j.gaceta.2021.11.003.
Objective:
To assess the effectiveness of the vaccine against SARS-CoV-2 (BNT162b2) in healthcare personnel of a health department.
Method:
Test-negative case̶control study. Healthcare personnel with suspected COVID-19 and healthcare personnel close contacts of COVID-19 cases were included between January 27th and June 6th, 2021. They were PCR tested for SARS-CoV-2; those with positive PCR were considered cases and those with negative PCR were considered controls. The adjusted vaccine effectiveness (aVE) to prevent COVID-19 cases and their 95% confidence interval (95%CI) were calculated using the formula VE=(1−odds ratio)×100.
Results:
624 healthcare personnel were included, of which 43 (6.9%) were considered cases and 581 (93.8%) controls. The aVE of the complete regimen was 96.3% (95%CI: 82.599.2). The aVE of the incomplete pattern was 68.0% (95%CI: 30.085.4).
Conclusions:
The administration of the complete pattern of BNT162b2 vaccine against SARS-CoV-2 is effective for the prevention of cases of COVID-19 in healthcare personnel.
Keywords : COVID-19; SARS-CoV-2; COVID-19 vaccines; Case control studies; Immunogenicity vaccine; Health personnel.
