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Cirugía Plástica Ibero-Latinoamericana

On-line version ISSN 1989-2055Print version ISSN 0376-7892


HERNANDEZ, I.; ROSSANI, G.  and  CASTRO-SIERRA, R.. Beneficial effect of fibrin autologous adhesive and PRP in rhytidectomy. Cir. plást. iberolatinoam. [online]. 2015, vol.41, n.3, pp.241-258. ISSN 1989-2055.

Our goal is to determine the clinical efficacy of autologous fibrin and PRP adhesive effect in reducing complications in rhytidectomy. Short, medium and long term patient recovery time was followed up. All patients received treatment with the autologous blood fractions on only half of the face, while the other half served as a control. Comparative follow up were observed in their post-op symptoms: frequency in developing hematomas, seromas, epidermolysis, necrosis and echymosis; patients were also requested to complete questionnaires regarding satisfaction with the outcome. We conduct a prospective, double blind, randomized clinical study in phase I, on a sample of 19 patients, over 50 years of age, who underwent surgical facial lifting (rhytidectomy), and were randomly exposed to autologous adhesive fibrin and PRP on half of the face, where received autologous fibrin and PRP by dripping on the whole surgical area including temples, cheeks and neck, before its closure. Treatment was completed with a laminar drainage for 24 hours, and occlusive bandage for 72 hours. The half faces treated with hemoderivatives presented less complications and progressed faster and better than those that were operated without them. Mean recovery time was 48% less than the half face not treated. Hematomas were observed only on the half faces not treated, and ecchymosis was also more evident on this side. Wound healing with epidermolysis of flap edges were present in 10 cases: 2 in a half face treated and 8 in control. The half faces treated progressed faster and with no scarring consequences. Patient satisfaction with results was high. In conclusion, autologous fibrin adhesive effect and PRP in rhytidectomies reduces the occurrence of seromas, ecchymosis, epidermolysis, and the recovery time; it obtains evident safe survival of flap edges and faster healing. Responses to questionnaire showed a high level of patient satisfaction with the results at short and medium point of control; but at longer following: 2 and 6 months, there were not visible differences between treated half faces versus the non-treated ones.

Keywords : Rhytidectomy; Fibrin adhesive; Autologous fibrin; PRP.

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