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Cirugía Plástica Ibero-Latinoamericana

On-line version ISSN 1989-2055Print version ISSN 0376-7892


SAMPIETRO-DE-LUIS, José-Manuel et al. Experience with NexoBrid® in enzymatic debridement of facial burns followed by conservative treatment with Medihoney®. Cir. plást. iberolatinoam. [online]. 2016, vol.42, n.3, pp.217-225. ISSN 1989-2055.

Background and Objective. Enzymatic debridement of burns has been studied for decades. In this theme, NexoBrid® (MediWound Ltd., Israel) is postulated as a promising alternative to classic surgical debridement of burns. Moreover, the antibacterial and healing properties of honey have been recently evaluated with good clinical results. This paper describes our preliminary experience with the use of NexoBrid® to treat burns in the facial area, followed by topical application of Medihoney® Wound Gel (Derma Sciences Ltd., USA). Methods. All patients received in our Burns Unit with dermal or subdermal facial burns affecting 2 or more aesthetic subunits were included in the study. Enzymatic debridement was performed with NexoBrid® in the first 24 hours. Subsequently, conservative management was carried on by topical cures with Medihoney® Wound Gel. Data about quality of debridement, the need for surgical debridement, time to complete epithelialization, presence of infection, and the need for corrective surgery of sequelae were collected. Results. Ten patients with facial burns of diverse etiology (flame, electric flash, deflagration, scald and chemical) were treated. The initial debridement was complete in all patients. Complete epithelialization was achived on an average of 13.88 days (10-20 days). No patient presented clinically apparent infection, and didn't require surgical debridement, coverage by autografts, nor surgery of sequelae. Conclusions. Our preliminary results indicate that the application of NexoBrid® and its combination with Medihoney® for the conservative management of facial burns seems feasible.

Keywords : Burns; Face; Facial; Enzimatic debridement; Bromelains; Manuka honey.

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