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Oncología (Barcelona)

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GOMEZ DE ANTONIO, D. et al. Complications of surgery after radiotherapy and adjuvant chemotherapy in non-small cell lung cancer: Analysis of a series of 16 patients. Oncología (Barc.) [online]. 2006, vol.29, n.2, pp.23-30. ISSN 0378-4835.

PURPOSE: To compare the postoperative morbimortality of patients with non-small cell lung cancer (NSCLC) patients treated employing a full dose of induction radiotherapy (>59 Gy) with those receiving a standard dose of radiotherapy (< 45 Gy). MATERIAL AND METHODS: A retrospective analysis of patients with NSCLC treated by surgery after chemo-radiotherapy ± chemotherapy in our institution since December 2000 (n=16) is made. Data about survival, postoperative morbidity, and time and site of recurrence or metastases are considered. RESULTS: There was no perioperative mortality. No statistical differences were found in postoperative morbidity when comparing both groups of radiation (p<0.197).The two years actuarial survival rate was 66.6 %. CONCLUSION: In our experience, it seems reasonable to offer surgery to patients with NSCLC even when they have received a full dose induction radiotherapy.

Keywords : Induction therapy; Surgery; Non-small cell lung cancer; Morbimortality.

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