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Revista Española de Enfermedades Digestivas

Print version ISSN 1130-0108


GUZMAN-DOMINGUEZ, G. et al. Seropositivity to Helicobacter pylori among university students and their families: A comparative cross-sectional study. Rev. esp. enferm. dig. [online]. 2008, vol.100, n.9, pp.540-544. ISSN 1130-0108.

Objective: to associate serologic response to Helicobacter pylori (Hp) among seropositive university students and their families in western Mexico. Methods: we conducted a comparative transversal study, and randomized 30 nuclear families of 14 Hp-seropositive university students and 14 Hp-seronegative university students. We carried out seropositivity measurements (IgG) to Hp using the ELISA method. An analysis was performed utilizing the chi-squared and Mann-Whitney U tests, with the aid of EPI INFO 2000 and SIGMA STAT 3.2 software. Results: global seropositivity in the families of infected students was 57 vs. 13% of the relatives of non-infected students (p = 0.000002). In families of Hp-positive students we found the following frequencies: parental (father and mother) 70%; mother 71%, and siblings 42%, while for seronegative individuals incidences were: parental 17% (p = 0.00005), mother 12% (p = 0.001), and siblings 10% (p = 0.0076). Conclusions: there is a greater prevalence of antibodies against Hp in the relatives of seropositive students.

Keywords : Helicobacter pylori; University students; Familial seroprevalence; Familial transmission.

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