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Revista Española de Enfermedades Digestivas

Print version ISSN 1130-0108


FERNANDES, Samuel Raimundo et al. Intrahepatic clear cell cholangiocarcinoma: an uncommon histologic subtype: case report and literature review. Rev. esp. enferm. dig. [online]. 2017, vol.109, n.5, pp.382-385. ISSN 1130-0108.

Clear-cell cholangiocarcinoma is a very uncommon variant of cholangiocarcinoma with a largely unknown natural history and prognosis. We report a case of a 51-year-old previously healthy woman presenting with a large liver nodule found on routine imaging. Needle biopsy of the lesion suggested a non-hepatocellular carcinoma. After extensive workup for other primary neoplasms, the patient underwent a partial hepatectomy. Histopathology was compatible with a moderately differentiated clear-cell cholangiocarcinoma. There was no evidence of liver disease in the remaining tissue. The patient underwent chemotherapy and remains in clinical remission after two years.

Keywords : Liver nodule; Intrahepatic cholangiocarcinoma; Clear-cell carcinoma.

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