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Revista Española de Cirugía Oral y Maxilofacial

On-line version ISSN 2173-9161Print version ISSN 1130-0558


OLMEDO DE LA CRUZ CARRANZA, Holger; ASMAT ABANTO, Ángel Steven  and  GUERRERO GUEVARA, Rember. Effectiveness of 4 and 8 mg prophylactic dexamethasone to control post-surgical swelling of impacted third molars: a randomized parallel-group clinical trial. Rev Esp Cirug Oral y Maxilofac [online]. 2013, vol.35, n.4, pp.157-161. ISSN 2173-9161.

Objective: To compare the effectiveness of 4 and 8mg prophylactic oral dexamethasone (PO) to control post-surgical swelling of impacted third molars. Material and methods: This randomized parallel-group clinical trial was conducted in the Dental Clinic of Universidad Privada Antenor Orrego (Trujillo - Peru), between August 2010 and March 2011. Patients who required extraction of impacted third molar were randomized into two groups: 27 received 4mg dexamethasone PO, and 27 received 8mg PO, according to established criteria. A standardized procedure was used, with effectiveness in controlling swelling by comparing pre- and post-operative facial measurements. Statistical analysis was performed using the t-test for comparison of means with a significance at 5%. Results: Greater effectiveness for controlling swelling was observed with 8mg of dexamethasone than with 4mg of dexamethasone. Patients in the 8mg group only showed effectiveness in controlling swelling in the reference angle of the jaw-tragus (P=.500), while was not effective for the other references. The same results were observed in the 4mg group (P=.163). Conclusion: Dexamethasone 8mg PO has greater effectiveness than 4mg to control postoperative edema of third molars.

Keywords : Third molars; Swelling; Dexamethasone.

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