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Revista Española de Cirugía Oral y Maxilofacial

On-line version ISSN 2173-9161Print version ISSN 1130-0558


AGEA MARTINEZ, Marc et al. Disseminated iatrogenic Kaposi's sarcoma with debut in the maxillary gingiva: a case report. Rev Esp Cirug Oral y Maxilofac [online]. 2021, vol.43, n.2, pp.55-58.  Epub Sep 13, 2021. ISSN 2173-9161.

Kaposi's Sarcoma (KS) is a multifocal neoplasm of cells derived from the lymphatic endothelium infected with the Human Herpes Virus 8 (HHV-8). Four clinical subtypes are described, which are histologically indistinguishable, differ in epidemiology and prognosis: classic, iatrogenic, endemic and epidemic. Involvement of the oral cavity is rare in the iatrogenic type and exceptional as a clinical debut. The diagnosis requires histological confirmation with immunohistochemistry. Oral involvement is associated with disseminated disease, with diagnostic suspicion and biopsy taking being essential for early diagnosis and correct staging, due to the important therapeutic and prognostic implications.

The clinical case of a 41-year-old male evaluated for a tumor in the attached gingiva with previous periodontal treatment and a history of kidney transplantation is described. Excisional biopsy was performed with a diagnosis of KS, which after completing the study confirmed disseminated iatrogenic-type KS requiring a change in immunosuppressive medication and 6 cycles of chemotherapy treatment with complete response.

Keywords : Kaposi sarcoma; iatrogenic Kaposi; periodontal disease; kidney trasplant; pyogenic granuloma.

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