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Revista Española de Cirugía Oral y Maxilofacial

On-line version ISSN 2173-9161Print version ISSN 1130-0558


CAUBET-SAEZ-TORRES, Ignacio; IBASETA-FIDALGO, Eduardo; RODRIGUEZ-COBO, Juan  and  GARCIA-REIJA, María Fe. Acquired Factor XIII deficiency as a cause of massive hemorrhage with upper airway compromise in oncological surgery of the oral cavity. Rev Esp Cirug Oral y Maxilofac [online]. 2023, vol.45, n.1, pp.50-53.  Epub June 26, 2023. ISSN 2173-9161.

The etiological diagnosis of persistent postoperative bleeding in adult patients with no relevant medical history is currently a challenge. Among the different causes, we find the acquired deficiency of Factor XIII (F. XIII) of coagulation. The deficit of this factor usually goes unnoticed as it is not tested in the routine preoperative studies. We present the case of a 70-year-old man with previously undiagnosed acquired F. XIII deficiency who, after undergoing surgery for squamous cell carcinoma of the floor of the mouth, suffered oral and bilateral cervical bleeding causing airway compromise.

Keywords : Postoperative bleeding; Factor XIII; airway compromise.

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