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Revista Española de Cirugía Oral y Maxilofacial

On-line version ISSN 2173-9161Print version ISSN 1130-0558


GUTIERREZ-BRAGHETTO, Sergio; NAVARRO-WIKE, Pablo  and  DONOSO-HOFER, Francisca. Oral manifestation of T-cell lymphoblastic lymphoma: an unusual and challenging case. Rev Esp Cirug Oral y Maxilofac [online]. 2023, vol.45, n.2, pp.83-87.  Epub Nov 20, 2023. ISSN 2173-9161.

Malignant neoplasms of lymphoid origin correspond to a complex group of diseases whose diagnosis is difficult since it requires the application of immunohistochemical tests, an exhaustive analysis by the histopathological team as well as a representative sample of the tissue to be examined. We present the case of a patient previously diagnosed with non-Hodgkin's lymphoma type T, with clinical manifestation in the oral cavity, who presented a poor response to the initial chemotherapeutic scheme. Due to the therapeutic failure, new biopsies and immunohistochemical analysis were requested, being the oral cavity sample the one that confirmed the diagnosis, this time correctly, of T-cell lymphoblastic lymphoma, thus modifying the initial therapeutic scheme to one of greater intensity, achieving a favorable evolution of the disease. The present article corresponds to the first case of T-cell lymphoblastic lymphoma with maxillary location reported in the literature. It emphasizes the diagnostic difficulty of the different types of lymphomas and highlights the importance of complementary examinations to achieve a correct diagnosis and management of this pathology.

We believe that this new, relatively simple technique can be an alternative to complex surgeries that involve the use of complicated bone grafts, with the consequent savings in time and morbidity for patients who associate maxillary hypoplasia and edentulism with severe bone atrophy.

Keywords : Lymphoma; T cell lymphoblastic lymphoma; maxillofacial; diagnosis.

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