SciELO - Scientific Electronic Library Online

vol.16 número4Aneurismas del sector distal de la arteria cerebral anterior (arteria pericallosa)Metástasis intramedular como primera manifestación de un carcinoma renal índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google



versión impresa ISSN 1130-1473


PINILLA-ARIAS, D. et al. Immunotherapy in high grade astrocytomas: principles and current state. Neurocirugía [online]. 2005, vol.16, n.4, pp.345-358. ISSN 1130-1473.

It is generally accepted that tumour development promotes a systemic response leading to protect the host against cancer. However, tumours may as well elicit a partial immunodeficiency to avoid the development of a complete and active immune response. Since Bloom´s first studies on immunotherapy to treat high grade gliomas in 1960, many attempts have been made from different medical specialties to use the immune system as a weapon against a great diversity of cancers. Main objective of this study is to outline the basic features of the immune response inside the Central Nervous System, the strategies employed by astrocytic tumours to evade body defences, and to provide an extended literature review on research on immunotherapy, especially concerning its patho-physiology and the clinical results achieved till date.

Palabras clave : Immunotherapy; Glioma treatment; Interleukin Lymphocytes.

        · resumen en Español     · texto en Español     · Español ( pdf )


Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons