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Print version ISSN 1130-1473


GARCIA-MARCH, G.; SANCHEZ-LEDESMA, M.J.  and  BROSETA, J.. Vagus nerve stimulation for the treatment of refractory epilepsy: State of the art. Neurocirugía [online]. 2008, vol.19, n.5, pp.416-426. ISSN 1130-1473.

The vagus nerve stimulation (VNS) therapy is a new neurostimulation technique used for treating pharmacoresistant epilepsy. It can be considered an effective and safe alternative for the treatment of refractory epilepsy patients. In the present review, we describe the surgical implantation technique, its indications and results achieved until now. We will also summarize the possible mechanisms of action of VNS therapy. Finally, we will comment on the difficulties and inconvenients that did not allow this antiepileptic surgical technique to become more widely used.

Keywords : Epilepsy; Vagus nerve stimulation; Save and efficacy; Action mechanisms.

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