Abstract

GASPAR CARRENO, M. et al. Recommendations for the preservation and good-for-use period of multi-dose containers after being opened. Farm Hosp. [online]. 2013, vol.37, n.6, pp.450-468. ISSN 2171-8695.  https://dx.doi.org/10.7399/FH.2013.37.6.829.

Objective: The aim of this work is to establish the standard procedure for use and preservation of drugs, dietary products and cosmetic products in multi-dose containers. Method: A summary table containing all the drugs, dietary and cosmetic products included in the hospital vademecum available in multi-dose containers was elaborated and information on preservation and good-for-use periods was gathered from the products technical sheets, consultation to the pharmaceuticals companies, and literature search. Results: 205 pharmaceutical specialties and magisterial formulations elaborated at the hospital were reviewed. A standardized working procedure was created with general instructions and a table of recommendations in case of missing information. Conclusions: with the present study, the information on the good-for-use period and preservation of multi-dose containers after being opened is improved. This information should always be kept available and updated.

Keywords : Multi-dose containers; Stability; Opening; Preservation of drugs; Hospital Pharmacy Department.

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