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Farmacia Hospitalaria

versión On-line ISSN 2171-8695versión impresa ISSN 1130-6343


MANZANO-GARCIA, Mercedes et al. Adequancy of treatment with canaglifozin alter alerts pharmacovigilance in the health management area. Farm Hosp. [online]. 2017, vol.41, n.5, pp.583-588. ISSN 2171-8695.


To analyze the impact of a strategy on the suitability of canaglizozin, and its level of acceptance, after issuing recommendations based on drug surveillance alerts issued by the Spanish Medicines and Medical Devices Agency (AEMPS).


A prospective intervention from may 2016 to october 2016.


South Seville Health Management Area.


Patients with active canagliflozin prescription.


The study was conducted in three phases, the first one linked to the issuance of the safety information note on the canaglifozin by the AEMPS, the obtaining of the patient lists and the recommendations of the adequacy in the sending of letters. A second phase where the medical professional performed the actions and a final phase in which the degree of acceptance of the recommendations made by the Pharmacy Service is evaluated.

Main measurements:

Suitability of canaglizozin treatment and the level of acceptance by physicians.


A total of 61 patients at baseline were included in treatment canagliflozin. Of the total number of patients referred to, some type of intervention was performed by the family and community medicine doctor after the pharmaceutical intervention (PI), by means of letters (n = 30), 56.7% were monitored, 33.3% were discontinued and 10.0% were closely monitored


Interventions aimed at reviewing patients on canagliptin, based on pharmacovigilance alerts, have been effective, with a high degree of acceptance by the family and community medicine practitioner.

Palabras clave : Canaglifozin; Alerts; Adequancy.

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