My SciELO
Services on Demand
Journal
Article
Indicators
- Cited by SciELO
- Access statistics
Related links
- Cited by Google
- Similars in SciELO
- Similars in Google
Share
Revista de la Sociedad Española del Dolor
Print version ISSN 1134-8046
Abstract
BANOS, J. E. and RUIZ-BARRIA, G.. Evaluation of experimental pain in the laboratory: models of neuropathic pain in animal's. Rev. Soc. Esp. Dolor [online]. 2006, vol.13, n.8, pp.542-552. ISSN 1134-8046.
In spite of the advancement of pain research in the last decade, the therapy of neuropathic pain is still an unresolved issue. Available treatments only adequately improve only a third of patients. Experimental models may contribute to the knowledge of its pathophysiology, as well as to the development of new drugs. Basically, two types of animal models are available: those that cause a lesion in the peripheral nerves and those that injury the central nervous system. Beyond these limitations, animal models may help to improve the knowledge of neuropathic pain and some of them have predictive value on the usefulness of analgesic efficacy of new drugs. Obviously, only well-designed, controlled clinical trials will permit to establish their actual efficacy in the clinical setting.
Keywords : neuropathic pain; experimental models; basic research.