Abstract

FERNANDEZ, S.; PELAEZ, R.  and  AGUILAR, J. L.. Drug therapy for chronic pelvic urogenital pain: a review of available evidence. Rev. Soc. Esp. Dolor [online]. 2011, vol.18, n.1, pp.56-63. ISSN 1134-8046.

Lack of consensus in definitions and scarce knowledge about urogenital system chronic pain physiopathology are some factors that explain the use of dozens of drugs, tested for its treatment and the lack of definitive therapy. There are many urinary bladder, reproductive tract and pelvic floor organic and functional pathologies that may be origin of pain. In this review we will focus on functional disorders where pain cannot be explained by a structural pathology or any other well-known factor. Current therapeutic options cover a wide range from acupuncture and physical therapy, psychological therapy, systemically or locally administered drugs, nervous blockades and sacral roots neuromodulation. Going on pharmacological therapy it is worth highlighting the multitude of drugs that had been tested for the treatment of these entities. Many clinical studies fail in its attempt of demonstrating benefit of different treatments currently used, maybe because many therapies are effective only in patients' subgroups. Effort should be focused on identifying these subgroups to help guiding its treatments. On the other hand, bearing in mind that in the urogenital and pelvic chronic pain different pathogenic mechanisms can exist together, a multidisciplinary approach is mandatory in order to implement a diversity of therapeutic modalities to obtain an optimal outcome.

Keywords : Chronic pelvic pain syndrome; Pharmacological treatment.

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