Abstract

AGUILERA EGUIA, R. et al. Levels of evidence and grades of recommendation (I): towards the GRADE perspective. Rev. Soc. Esp. Dolor [online]. 2014, vol.21, n.2, pp.92-96. ISSN 1134-8046.  https://dx.doi.org/10.4321/S1134-80462014000200006.

Nowadays, it is being important to take clinical decisions based on the best levels of evidence and grades of recommendation because both concepts are a fundamental pillar of evidence-based practice. Currently we can count over a hundred tools, 19 systems to assess the quality and 7 to grade the recommendations, the scales can use letters (A, B, C, etc.), numbers (I, II, III) or a combination of both (Ia, IIb, IIa, etc.) but the way to express the levels of evidence and grades of recommendation is quite unequal among different scales, showing differences in the criteria of graduation, reproducibility, and interpretation of the grades of recommendation, that can confuse and increase the uncertainty when making a clinical decision. The purpose of our work is to show the initiatory GRADE.

Keywords : Systematic reviews; Clinical practice guidelines; Health technology assessment; Quality of evidence; Strength of recommendations.

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