Abstract

MOORE, Keith  and  GRAY, David. The use of the antimicrobial agent PHMB to prevent wounds infection. Gerokomos [online]. 2008, vol.19, n.3, pp.145-152. ISSN 1134-928X.

Post-operative wound infections may result in delayed healing, extended hospital stay and increased costs. The increase in antibiotic-resistant bacteria mitigates against the prophylactic use of antibiotics. An effective alternative is the use of antiseptics that are less likely to generate resistance. AMD^TM wound dressings use polyhexamethylene biguanide (PHMB) which has a low toxicity for wound cells and is effective in killing antibiotic-resistant bacteria. This paper reviews the evidence for the efficacy and cost-effectiveness of AMD dressings in the prevention of surgical site infections when routinely used in standard wound care protocols.

Keywords : AMD^TM wound dressings; cost-effectiveness; MRSA; polyhexamethylene biguanide (PHMB); wound infection.

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