Abstract

CASTILLO CARRION, Paula; LIRIA SANCHEZ, Pedro Jorge  and  GERONIMO-PARDO, Manuel. Off-label topical sevoflurane as an alternative treatment for a pressure ulcer in a frail patient. Gerokomos [online]. 2020, vol.31, n.4, pp.268-270.  Epub Feb 08, 2021. ISSN 1134-928X.  https://dx.doi.org/s1134-928x2020000500013.

A frail tetraparetic patient suffered from a sacral pressure ulcer which had been refractory to conservative topical treatment, consisting in postural hygiene and application of silver sulfadiazine cream. A gluteal flap surgery had been scheduled but, due to the high anesthetic risk, the patient was offered to try to heal the ulcer with topical sevoflurane, which was accepted. Sevoflurane was daily applied at home, and the wound condition successfully improved, showing a progressive reduction in its size and deepness until it was considered fully healed after few weeks; as a consequence, the scheduled surgery was avoided. Off-label use of topical sevoflurane on complicated wounds seems to be valuable, since it represents a noninvasive alternative and it is very easy to perform.

Keywords : Sevoflurane; topical administration; pressure ulcer; local anti-infective agents; wound healing; paraplegia.

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