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Revista Española de Salud Pública

On-line version ISSN 2173-9110Print version ISSN 1135-5727


MENDOZA-GARCIA, José L. et al. Impact of nosocomial transmission of influenza virus in an acute hospital. Rev. Esp. Salud Publica [online]. 2018, vol.92, e20180814.  Epub Aug 10, 2018. ISSN 2173-9110.


The increase in morbidity and mortality associated the influenza virus infections represents an important global challenge, with particular relevance within health institutions. The aim of the study was to highlight the impact, repercussions and characteristics of the nosocomial transmission of influenza virus.


A sample of 286 hospitalized patients in a third-level hospital with confirmed influenza (virus RNA in respiratory specimens) is included. The study design was observational, through the collection of positive microbiological results from the 2016-2017 season. A comparative statistical analysis was carried out between cases of community-acquired influenza and hospital-acquired cases.


14.3% of the total sample (41 cases) was considered of nosocomial origin. Significant differences were observed in the percentage of vaccinated between hospital-acquired (34.1%) and community-acquired (50.2%); and in the number of days of hospitalization after diagnosis between both groups. The attack rate was 0.66%.


The nosocomial acquisition of the influenza virus resulted in a greater severity of the process and in the increase of days of hospital stay. Strict adherence to control measures and epidemiological surveillance of influenza cases has allowed to reduce the attack rate.

Keywords : Cross infection; Influenza A virus; Influenza Vaccines; Vaccines; Infection Control; Polymrase Chain Reaction.

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