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Anales del Sistema Sanitario de Navarra

versión impresa ISSN 1137-6627


LANDIN, I; BARBERIA, E; DASI, C  y  ARIMANY-MANSO, J. Unexpected death due to eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome). Anales Sis San Navarra [online]. 2019, vol.42, n.1, pp.83-87.  Epub 21-Oct-2019. ISSN 1137-6627.

Eosinophilic granulomatosis with polyangiitis (EGPA), or Churg-Strauss syndrome, is a rare disease characterized by disseminated necrotizing vasculitis with extravascular granulomas occurring among patients with asthma and tissue eosinophilia. Clinically, it presents in various ways and progresses in three phases: prodromic (asthma and rhino-sinusitis), eosinophilic (peripheral eosinophilia and organ involvement), and vasculitic (clinical manifestations due to small vessel vasculitis). The differential diagnosis of EGPA principally includes eosinophilic and vasculitic disorders, early treatment is needed to avoid a fatal outcome.

We present the case report of a 38-year-old male with a history of asthma. After a month-and-a-half of progressive weakness, no fever, diarrhea, vomiting and abdominal pain associated with weight loss, he was diagnosed of intestinal parasitosis. He later died of a massive myocardial necrosis due to EGPA with multiple organs affected.

Palabras clave : Churg-Strauss syndrome; Eosinophilic granulomatosis with polyangiitis; Hipereosinophilia; Vasculitis.

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