Abstract

DOMINGUEZ TRISTANCHO, Carmen; MACHADO GUZMAN, Visitación; MARQUEZ BENITEZ, Jesús  and  GOMEZ AINSUA, Cristina. Incidence of peritonitis caused by oxacillin-cephazolin resistant germs in peritoneal dialysis. Rev Soc Esp Enferm Nefrol [online]. 2005, vol.8, n.3, pp.51-54. ISSN 1139-1375.

Coagulase-negative Staphylococcus and Staphylococcus aureus continue to the germs most often responsible for peritonitis in patients treated using peritoneal dialysis. A variable portion of these germs have developed resistance to antibiotics such as oxacillin, cephazolin and glycopeptides. A total of 75 cases of peritonitis occurring in the last 5 years in 38 patients were analysed, to determine the percentage of gram positive germs resistant to oxacillin-cephazolin and to describe the evolution of these cases of peritonitis with empirical treatment with teicoplanine-cephtazidime, investigating the distinctive characteristics with respect to cases of peritonitis caused by germs that are sensitive to these antibiotics. The results of the cultures were: sterile 15%, coagulase negative Staphylococcus 37%, Staphylococcus aureus 8%, gram negatives 23%, other gram positives 13% and others 4%. No resistance to teicoplanine was found in any of the gram positive germs, nor to cephtazidime in the gram negatives; however, 50% of Staphylococcus were resistant to oxacillin and cephazolin. The percentage curation rate was over 90%, it not being possible to determine any distinguishing characteristics. In conclusion, the high curation rate in gram positive peritonitis treated with teicoplanine-cephtazidime is a further argument in favour of validating this treatment as the choice in peritoneal dialysis peritonitis.

Keywords : Peritoneal dialysis; Peritonitis; Teicoplanine-Cephtazidime.

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