SciELO - Scientific Electronic Library Online

vol.8 issue2Intracellular inclusions of uncultured magnetotactic bacteriaAntibacterial activity of cerein 8A, a bacteriocin-like peptide produced by Bacillus cereus author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


International Microbiology

Print version ISSN 1139-6709


TONKIC, Marija; GOIC BARISIC, Ivana  and  PUNDA-POLIC, Volga. Prevalence and antimicrobial resistance of extended-spectrumb-lactamases-producing Escherichia coli and Klebsiella pneumoniae strains isolated in a university hospital in Split, Croatia. INT. MICROBIOL. [online]. 2005, vol.8, n.2, pp.119-124. ISSN 1139-6709.

The prevalence of Escherichia coli and Klebsiella pneumoniae that produce extended-spectrumb-lactamases (ESBL) was investigated in patients of a university hospital in Split, Croatia. Patients were grouped according to age (pediatric vs. adult), antibiotic type, and hospital ward. From Jan. 2001 to Dec. 2002, the susceptibility of E. coli and K. pneumoniae isolates to antimicrobials was tested. ESBL production was assayed using the double-disk synergy test. ESBL-producing E. coli and K. pneumoniae were detected in all sites of infection sampled. The percentages of ESBL-positive isolates were higher in the pediatric wards than in the adult wards. The antibiotics most commonly prescribed to patients in all hospital wards belonged to the third-generation cephalosporin group. Among ESBL producers, E. coli isolates were more resistant to aminoglycosides, but less resistant to ciprofloxacin and cotrimoxazole. Resistance of E. coli and K. pneumoniae to ciprofloxacin was exclusively found in isolates from adult patients. None of the isolates, regardless of ESBL production, was resistant to carbapenemes. In addition, the prevalence and antimicrobial resistance of ESBL-producing E. coli and K. pneumoniae isolates differed between pediatric and adult patients.

Keywords : Escherichia coli; Klebsiella pneumoniae; resistance; extended-spectrumb-lactamases (ESBL).

        · abstract in Spanish | Portuguese     · text in English     · English ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License