Abstract

DISCEPOLI, N.; COSTA BERENGUER, X.  and  BASCONES-MARTINEZ, A.. Regenerative procedure for intra-bony periodontal defects: Combination of barrier membrane and filling material, clinical and preclinical evidence. Avances en Periodoncia [online]. 2012, vol.24, n.3, pp.145-150. ISSN 2340-3209.

Regenerative periodontal therapy aims to predictably restore the tooth's supporting periodontal tissues and should result in formation of a new connective tissue attachment (i.e. new cementum with inserting periodontal ligament fibres) and new alveolar bone. Histologic evidence from preclinical models has demonstrated periodontal regeneration following treatment with barrier membranes, various types of grafting materials or a combination thereof. However, it is still not clear to what extenta combination of barrier membranes and grafting materials may additionally enhance the regeneration process compared with barrier membranes alone, grafting materials alone or open flap debridement.

Keywords : Animal models; barrier membranes; grafting materials; histology; preclinical models; regenerative periodontal therapy.

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