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Revista Clínica de Medicina de Familia

On-line version ISSN 2386-8201Print version ISSN 1699-695X


CARCELLER RUIZ, Mª Ángeles; VERA MONTES DE OCA, Antonia; BLANCO DE LA RUBIA, Mª Jesús  and  LEON MARTIN, Antonio Alberto. Dysphonia and Lumbago as signs of Granulocytic Sarcoma: Initial manifestation of Acute Myeloid Leukaemia. Rev Clin Med Fam [online]. 2009, vol.2, n.7, pp.368-370. ISSN 2386-8201.

Granulocytic sarcoma or chloroma is an extramedullar tumor consisting of primitive granulocytic cells. It has been described in patients with acute leukaemia and chronic myeloproliferative syndromes transforming into leukaemia. It is rare and generally an initial manifestation of leukaemia. Diagnosis is based on suspicion and is always difficult if it is not considered in the differential diagnosis procedure because the clinical manifestations in the affected area often mask their aetiology. We contribute the case of a 78 year old man who was referred to the hospital emergency department from his primary care centre for evaluation. He had suffered from dysphonia, lumbago and general malaise for a month and had not responded to conventional treatment.

Keywords : Voice Disorders; Low Back Pain; Sarcoma, Myeloid; Leukemia, Myeloid, Acute.

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