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Revista Clínica de Medicina de Familia

On-line version ISSN 2386-8201Print version ISSN 1699-695X


GONZALEZ SILVA, Yolanda et al. Utility of the Charlson Comorbidity Index in older people and concordance with other comorbidity indices. Rev Clin Med Fam [online]. 2021, vol.14, n.2, pp.64-70.  Epub July 26, 2021. ISSN 2386-8201.


The main aim of our study was to evaluate the current usefulness of the CCI in predicting mortality in older people and the concordance between various comorbidity indices.


An observational, concurrent cohort study was performed.


Internal Medicine Service of a tertiary hospital, outpatients in a health centre and residents in four nursing homes.


375 individuals ≥65 years and with expected survival ≥6 months, without cognitive impairment.

Main measurements:

Three indices, the CCI, the Geriatric Index of comorbidity (GIC), and the Kaplan-Feinstein index (KFI), were administered in all participants. At 12 months, mortality was evaluated. The data were analyzed using the SPSS 23.0 statistical programme.


Average age 81.4 years. The CCI revealed low-medium comorbidity in the outpatient group aged 65-75: 43 (75.4%), moderate-high morbidity and more common in hospitalized patients: 19 (61.3%) and nursing homes: 5 (62.5%). At one year follow-up 59 (16.1%) individuals died: CCI: 10 (6.4%) low-medium and 49 (23.3%) moderate-high comorbidity, OR 3.63 (95% CI 1.76-7.51); KF: 27 (13.3%) low-medium and 32 (19.5%) moderate-high comorbidity, OR 1.38 (95% CI 0.78-2.44) and GIC: 45 (14.1%) low-medium and 14 (29.2%) moderate-high comorbidity, OR 2.47 (95% CI 1.21-5.06). The concordance between CCI-KF: 65-75 years K=0.62, 76-85 years: K=0.396 and ≥86 years: K=0.255. Concordance between CCI-GIC was: 65-75 years K=0.202, 76-85 years: K=0.069 and ≥86 years: K=0.118.


CCI was found to be the best predictor of mortality after one year of follow up. There was considerable concordance between CCI and KF in the 65-75 years and remaining age groups. Correlation with GIC was low.

Keywords : Comorbidity; Frail elderly; Mortality.

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