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Revista Clínica de Medicina de Familia

On-line version ISSN 2386-8201Print version ISSN 1699-695X


SOLANA LOPEZ, Irene; IZQUIERDO MARTINEZ, Aida  and  LOSADA VILA, Beatriz. Eaton lambert syndrome: a rare clinical presentation that usually precedes oncological diagnosis. Rev Clin Med Fam [online]. 2022, vol.15, n.1, pp.60-62.  Epub Apr 04, 2022. ISSN 2386-8201.

Eaton Lambert syndrome is an autoimmune disorder that involves the neuromuscular junction. Clinical course includes proximal muscular weakness and symmetry. In 60% of cases this is associated with underlying neoplasia. Given that this weakness is of insidious onset, patients usually initially consult their family doctor. Recognizing this condition is essential for early diagnosis of oncological disease as it usually occurs a few months prior to local symptoms arising from tumour disease. The family doctor plays a crucial role in early diagnosis and should refer early to hospital to complete the study. We report a case study of paraneoplastic Eaton Lambert syndrome in the context of a small cell lung carcinoma that tries to depict this chronology, in addition to tackling the diagnostic and therapeutic process.

Keywords : Lambert-Eaton myasthenic syndrome; neuromuscular junction diseases; paraneoplastic syndromes; small cell lung carcinoma.

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