SciELO - Scientific Electronic Library Online

vol.19 número2Semáforo nutricional: conocimiento, percepción y utilización entre los consumidores de Madrid, EspañaLa alimentación en los viajes espaciales tripulados: desde el Programa Gemini hasta la ISS/Shuttle índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados




Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google


Revista Española de Nutrición Humana y Dietética

versão On-line ISSN 2174-5145versão impressa ISSN 2173-1292


BERNACER, Raquel; ROIG, Diana  e  LOZANO, Blanca. Plant sterols for adults with hypercholesterolemia treated with or without medication (statins). Rev Esp Nutr Hum Diet [online]. 2015, vol.19, n.2, pp.105-115. ISSN 2174-5145.

Hypercholesterolemia is the most common coronary risk factor among the Spanish population; 37.4% of the Spanish adult population have cholesterol levels between 190 and 240 mg/dl. Foods enriched with plant sterols (PS) can effectively reduce plasma cholesterol in patients with high levels. However, its effectiveness and safety in adults with moderate hypercholesterolemia who are on medication (statins) or not has been less studied. The aim of this review is to establish the possible role of plant sterols in the control of hypercholesterolemia, as well as how safe they are for people with moderate hypercholesterolemia treated with statins. The main studies were looked at, regardless of design, language or publication date which studied the connection between "plant sterols" and "hypercholesterolemia", using Pubmed/Medline, SCOPUS and Google Scholar databases. The studies brought together in this review show that an intake of between 2 and 3g/day of plant sterols effectively reduces plasma cholesterol levels in patients with hypercholesterolemia. Both clinical studies and available meta-analyses do not indicate any problems related to the drug-nutrient interaction associated with the use of plant sterol-enriched foods. In patients with moderate hypercholesterolemia where the use of statins is not justified a healthy diet, exercise and foods high in PS can provide the best therapeutic approach.

Palavras-chave : Hypercholesterolemia; Phytosterols; Plant Sterols; Functional Food; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Statins.

        · resumo em Espanhol     · texto em Inglês     · Inglês ( pdf )


Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons