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Enfermería Nefrológica

versión On-line ISSN 2255-3517versión impresa ISSN 2254-2884


GUILLEN-GOMEZ, Irene; BLANCO-GARCIA, Marina; ARANEGA-GAVILAN, Susana  y  CRESPO-MONTERO, Rodolfo. Neoplastic alterations in the renal transplant patient. A systematic review. Enferm Nefrol [online]. 2022, vol.25, n.3, pp.204-215.  Epub 05-Dic-2022. ISSN 2255-3517.


Renal transplantation has been considered the best renal replacement therapy for end-stage chronic kidney disease, even though it carries a number of risks among which cancer is increasingly prominent. Therefore, it is necessary to determine the impact on this population.


To understand and synthesise the scientific evidence on the incidence of neoplasms in renal transplant patients, as well as the related variables.


A systematic review was carried out including 14 articles from Pubmed, Scopus, Scielo, Web of Science and Google Scholar databases. The MeSH terms used were: neoplasms, kidney transplantation, incidence, risk, risk factors. Original articles written in English and Spanish, studying adult transplanted population were included.


Fourteen articles with observational design were included. The main variables that emerged from the review were: overall incidence, demographic data and previous treatments, other associated characteristics, most frequent tumours and preventive measures.


TThe incidence of neoplasms in transplant patients is high, especially in the older age group and in patients with immunosuppressive treatment with cyclosporine and azathioprine; the latter, together with transplantation from cadaver, being the main risk factors found. Non-melanoma skin cancers are the most prevalent and prevention measures include routine screening, promotion of a healthy lifestyle, and promotion and enhancement of hepatitis B vaccination.

Palabras clave : neoplasms; kidney transplantation; incidence; risk factors.

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