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Ars Pharmaceutica (Internet)

On-line version ISSN 2340-9894


ROMERO OTERO, Mónica et al. Use of heat-denatured 99mTc-labeled red blood cells in the scintigraphic diagnosis of an infrequent case of intrathoracic splenosis. Ars Pharm [online]. 2018, vol.59, n.4, pp.259-262.  Epub Oct 19, 2020. ISSN 2340-9894.

Intrathoracic splenosis is extremely rare and is associated with previous history of rupture of the spleen and diaphragm caused by trauma. It is usually asymptomatic, presenting as an accidental finding in the X-ray images or computed tomography.

The definitive diagnosis can be made by scintigraphic studies associated with functional studies of particle or cell uptake. Due to its sensitivity and specificity, gammagraphy with heat-denatured 99mTc-labeled red blood cells is the reference technique for confirming the diagnosis of splenosis and differentiating it from other processes that require surgical resection.

We describe the case of a 52-year-old man treated for pleuritic pain in the left hemithorax. The images showed left pleural effusion and pulmonary infarction without signs of thromboembolism. There were multiple foci suggestive of splenosis, which was confirmed by splenic scintigraphy with heat-denatured 99mTc-labeled red blood cells.

Keywords : Intrathoracic splenosis; Scintigraphy; Radionuclide imaging.

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