SciELO - Scientific Electronic Library Online

vol.63 número1Skeletal muscle relaxant activity of different formulation of span 60 niosomesRelación entre el control de la presión arterial y la adherencia al tratamiento medida mediante el sistema de receta XXI en Granada (España) índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google


Ars Pharmaceutica (Internet)

versión On-line ISSN 2340-9894


SAAVEDRA-SUAREZ, Segundo et al. Comparative study of the biopharmaceutical quality of Diazepam 10 mg commercialized in the Peruvian market. Ars Pharm [online]. 2022, vol.63, n.1, pp.45-55.  Epub 21-Mar-2022. ISSN 2340-9894.


diazepam belongs to a group of medicines called benzodiazepines. These drugs are known to work in the brain through GABA and, it used to relieve anxiety and control the agitation caused by alcohol withdrawal.


variation in weight, friability, hardness, disintegration time, quantification of active ingredient, speed and dissolution profile between the innovative and multi-source drugs marketed in the Peruvian market. The evaluation of these presentations did with the USP 42 Pharmacopeia.


the results established that all Diazepam 10 mg multi-source tablets included in this research are bioequivalent with the chosen innovative brand and, therefore, can be interchangeable.


The results observed that the multi-source tablets of Diazepam 10 mg included in this research are bioequivalent with the innovator and, therefore, allow the determination of pharmaceutical equivalence as a support element in the decision-making process for purchasing in the service pharmacist.

Palabras clave : diazepam; interchangeability; bioequivalence.

        · resumen en Español     · texto en Español     · Español ( pdf )