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Ars Pharmaceutica (Internet)

On-line version ISSN 2340-9894


PAREJA-MARTINEZ, Elisa; ESQUIVEL-PRADOS, Elisabeth; MARTINEZ-MARTINEZ, Fernando  and  GARCIA-CORPAS, José P. Relationship between blood pressure control and treatment adherence measured using the electronic prescription in Granada (Spain). Ars Pharm [online]. 2022, vol.63, n.1, pp.56-71.  Epub Mar 21, 2022. ISSN 2340-9894.


Treatment adherence has been identified as one of the most relevant factors in achieving adequate blood pressure values in hypertensive patients. Aims: To describe patient adherence to antihypertensive treatment determined by drug collection records of the electronic prescription system and study the relationship between this adherence and blood pressure control.


Cross-sectional study conducted from May 2017 to May 2019, in 6 community pharmacies in the province of Granada (Spain). Patients over 18 years of age who took at least one antihypertensive medication for at least six months were included. Main outcome measure: Blood pressure control and adherence to antihypertensive treatment using the electronic prescription.


A total of 95 patients were included in the study. A total of 49 patients (51.6%) showed no blood pressure control, and 29 patients (30.5%) showed suboptimal adherence. The multivariate analysis showed no association between the degree of adherence and the variables included in the study, and blood pressure control was only related to sex (OR: 0.044; 95%CI: 0.005-0.427), to cardiac arrhythmia (OR: 0.004; 95% CI: 0.000-0.106) and to anxiety (OR: 0.109; 95% CI: 0.013-0.933).


The prevalence of uncontrolled blood pressure was very high (51.6%), and no association with common sociodemographic risk factors, such as physical activity, smoking, or body mass index, was found. Non-adherence to treatment also had a very high prevalence (30.5%), but it was not associated with disease control.

Keywords : Community Pharmacy Services; Electronic Prescription; High blood pressure; Treatment Adherence; Pharmaceutical Services; Pharmacies.

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