Resumen

PENADES, Bruno F; LOPEZ-OLIVA, Sara; TERREN-LORA, Ana  y  SAN MAURO-MARTIN, Ismael. Akkermansia muciniphila abundance according to BMI in patients with GI disorders: cross-sectional cohort pilot study. JONNPR [online]. 2023, vol.8, n.4, pp.618-626.  Epub 25-Oct-2024. ISSN 2529-850X.  https://dx.doi.org/10.19230/jonnpr.5332.

In recent years, Akkermansia muciniphila has gained prominence in scientific research due to its potential contribution to the regulation of immune response, insulin sensitivity, prevention of inflammatory diseases, and metabolic health. Specifically, its abundance has been inversely correlated with body weight, and its presence may have a beneficial effect on metabolism regulation. The aim of this study was to examine whether A. muciniphila was associated with BMI in individuals with gastrointestinal disorders. The results suggest that the abundance of A. muciniphila is very low in patients with gastrointestinal disorders (1.35%) and lower in individuals with overweight or obesity, although the results were not significant. This study could not confirm in a statistically significant way the hypothesis of the relationship between Akkermansia and overweight or obesity. Which may suggest either a lower power of the effect than expected, or no direct or causal relationship.

Palabras clave : Akkermansia muciniphila; Body Mass Index; obesity; gut microbiota; 16S rDNA.

        · resumen en Español     · texto en Español     · Español ( pdf )